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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX1
All Species:
17.88
Human Site:
S965
Identified Species:
35.76
UniProt:
Q9NRD9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD9
NP_787954.1
1551
177235
S965
S
Q
D
M
I
C
P
S
P
R
V
S
A
R
C
Chimpanzee
Pan troglodytes
XP_001163196
1551
177072
S965
S
Q
D
M
I
C
P
S
P
R
V
S
A
R
C
Rhesus Macaque
Macaca mulatta
XP_001111340
1551
176921
S965
S
Q
E
M
I
C
P
S
P
R
V
S
A
H
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001092767
1551
177113
S965
S
Q
E
K
I
C
P
S
P
R
M
S
A
H
C
Rat
Rattus norvegicus
Q8CIY2
1551
177179
S965
S
Q
E
K
I
C
P
S
P
R
M
S
A
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
I961
P
D
I
F
R
Q
N
I
N
N
R
I
S
F
L
Chicken
Gallus gallus
XP_425053
1523
173782
K937
N
R
V
S
F
I
K
K
D
M
S
L
P
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
H755
I
V
E
T
F
F
K
H
A
F
S
K
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
L888
G
M
F
Q
D
V
G
L
E
H
K
N
H
L
T
Honey Bee
Apis mellifera
XP_624355
1492
172466
E904
M
F
Q
D
A
G
L
E
R
K
D
Y
L
T
Y
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
Y908
L
F
N
E
V
L
H
Y
A
G
V
S
N
D
A
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
R1088
G
A
A
T
V
I
R
R
G
N
L
N
S
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.7
N.A.
N.A.
91
90.1
N.A.
73.9
65.1
N.A.
47.1
N.A.
39.9
40.3
34.3
41.6
Protein Similarity:
100
99.4
97.8
N.A.
N.A.
95
94.4
N.A.
84.4
78.4
N.A.
61.7
N.A.
58
60.2
55.9
59.3
P-Site Identity:
100
100
86.6
N.A.
N.A.
73.3
73.3
N.A.
0
0
N.A.
0
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
86.6
86.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
6.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
9
0
0
0
17
0
0
0
42
0
17
% A
% Cys:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
42
% C
% Asp:
0
9
17
9
9
0
0
0
9
0
9
0
0
9
9
% D
% Glu:
0
0
34
9
0
0
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
17
9
9
17
9
0
0
0
9
0
0
0
9
0
% F
% Gly:
17
0
0
0
0
9
9
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
9
0
9
0
0
9
25
0
% H
% Ile:
9
0
9
0
42
17
0
9
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
17
0
0
17
9
0
9
9
9
0
0
0
% K
% Leu:
9
0
0
0
0
9
9
9
0
0
9
9
9
25
9
% L
% Met:
9
9
0
25
0
0
0
0
0
9
17
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
9
0
9
17
0
17
9
0
0
% N
% Pro:
9
0
0
0
0
0
42
0
42
0
0
0
9
0
0
% P
% Gln:
0
42
9
9
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
0
9
9
9
42
9
0
0
25
0
% R
% Ser:
42
0
0
9
0
0
0
42
0
0
17
50
17
0
9
% S
% Thr:
0
0
0
17
0
0
0
0
0
0
0
0
0
9
9
% T
% Val:
0
9
9
0
17
9
0
0
0
0
34
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _